The Meridian Water scheme will create a new mixed-use community along the local waterways worth £1.3bn.
The masterplan from LDA Design includes 5,000 new homes alongside three schools and a range of supporting community facilities, a new high street shopping centre and a diverse parkland landscape.
A central causeway will be the backbone of the scheme linking Edmonton Green to the Lee Valley Regional Park and beyond.
Meridian Water will also deliver improvements to public transport that include a centrally located transport hub linked with Angel Road Station, redirected bus routes and proposals for improved rail services on the line connecting the area to Liverpool Street and Stratford.
Public consultation on the masterplan will run until August 3.
Enfield Council’s Cabinet Member for Business and Regeneration, Cllr Del Goddard, said: “This project will create a fantastic waterfront development that people will be proud to call their home and it will play a significant role in driving the expansion of North London for decades to come.
“This will be one of the biggest development opportunities in the UK and the whole project will provide a massive boost to Enfield, London and the South East.”
Colin James, Director of Urban Design at LDA Design, said: “This masterplan is the first step towards bringing forward Enfield Council’s vision for creating new high quality, energy efficient housing and breathing new life into employment areas.
“With an emphasis on sustaining strong business and economic growth, these plans are set to revitalise the site and create opportunities to attract new investment and facilities with a particular focus on green industries.
“As well as ensuring the proposal is commercially viable, we have taken inspiration from the waterways of the Lower Lee Valley as the plans have developed, and the aim here is to give people the experience of waterside living and working while being in easy reach of the rest of the city through better transport links.”