The high-density Peel Precinct development features seven new buildings, including a landmark 16-storey tower.
As well as more than 200 flats, the partners will also deliver a new health centre, pharmacy, cafe and retail space.
Architect Penoyre & Prasad has restored much of the area’s historic street pattern within the regeneration scheme.
Under the current plan, it will be built in three phases and forms part of a wider £400m regeneration of South Kilburn.
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Phase 1 requires demolition of the South Kilburn Studios to allow the first 38 lower rise affordable units to be constructed in Block E, housing all secure tenants currently remaining on the Peel site.
The structural engineer is Price & Myers, with mechanical and electrical engineering services provided by XCO2 Energy.