The larger of the two projects is a £48m, 363-apartment scheme set over two towers of 16 and 19 storeys in the Cornbrook area of Manchester.
ISG will also deliver a £24m, nine-storey, 200-unit development in the Baltic Triangle area of Liverpool.
The Cornbrook scheme comprises one and two-bedroom units, as well as duplex and townhouse apartments. It also includes a co-working space, a library, gym, two rooftop gardens and resident lounges.
Both tower blocks will incorporate a slipform concrete core and traditional brick façade, with undercroft car parking and raised courtyards.
Enabling works are underway with main work expected to start on site in November, with completion scheduled for autumn 2020.
Within Liverpool, ISG will deliver a nine-storey steel frame and brick-clad structure, with two levels of car parking.
The 200-units comprise one, two and three-bedroom apartments, and residents will benefit from a landscaped upper floor terrace, gym, lounge and concierge service. The development also includes commercial space at ground floor level.
Work is due to commence in October and scheduled for completion in summer 2020.
Paul Munro, regional director for ISG’s north west business, said: “This appointment showcases our capability to deliver high-value projects in our core cities as we continue to contribute to the ever-changing skylines across Manchester and Liverpool.”