Harris played a significant role in helping to steer the group through a major restructuring process and saw the firm return to profit last year after several years of losses.
He also played a part in establishing the strategic partnership with South African construction group Wilson Bayly Holmes Ovcon, which invested £12m in June 2017 for a 40% stake in the business.
The strategic investment strengthened Byrne’s balance sheet enhancing the firm’s ability to secure work.
WBHO has extended its interest to take a majority stake in the group while at the same time also taking a controlling stake in North West contractor Russells Construction.
Harris will not be replaced under the present management structure.
Michael Byrne, chief executive at Byrne Group, said: “The strengthening of the group’s activities and its financial position has meant that Daren’s role has changed significantly from when he took up his appointment.
“I’d like to thank Daren for his commitment to the group and being an integral part of our management team during a very challenging period.
“The Group remains one of the most respected contractors in our sector and we continue to build a strong forward pipeline of new work.”