Harrington said the “government’s approach to Brexit is playing roulette with the lives and livelihoods of the vast majority of people in this country.”
He added: “The clear message I have been receiving from the business community is that the failure to secure a deal and to rule out a hard Brexit is resulting in cancelled investment decisions, business being placed abroad and a sense of ridicule for British business across the world.”
MPs voted to take control of the Brexit process last night in a bid to find a Commons majority on a Brexit option.
Thirty Tory MPs voted against the Government including three ministers.
Harrington added: “I fear the no deal would be part of a giant economic experiment that is championed by a small minority of the economics profession, a small minority of the Conservative party and a small minority of the country.”
Harrington has been construction minister since 2017.