This latest deal gives Mount Anvil a pivotal role in transforming the area, following a separate agreement last month between Mount Anvil and Workspace for an £80m scheme at Wandsworth Business Village.
The privately company, led by chief executive Killian Hurley, has now purchased Cockpen House, which comes with planning approval for a £75m mixed-use scheme.
Work on site will start this summer with completion pencilled in for autumn 2014.
The former office and warehous site forms a strategic point in the town centre regeneration area, creating new pedestrian links through the town centre, together with smart ground floor shops and offices.
It will also include four tall residential blocks rising up to 16 storeys, with balconies, terraces and podium level gardens, delivering 207 homes with 184 homes for private sale.
The 23 affordable homes in the scheme will be handled by One Housing Group.
Hurley said: “This latest deal creates a major role for Mount Anvil in the regeneration plans for Wandsworth.
“We worked closely with Workspace on this deal as the two sites are next to each other and together represent a comprehensive development, enhancing both residential values and rents for the new Workspace facility.”