The Trinity Quay scheme was originally given the go-ahead more than two years ago but work never began on the scheme.
Up to 500 jobs could be created during construction of the hotel and conference centre.
Developer Fulstow Holdings has revealed plans to build a four-star hotel and conference centre overlooking the River Hull.
The London-based developer said it was now on the hunt for a contractor to build the 200-room hotel after Radisson Blu said it would operate the scheme.
The Trinity Quay scheme was originally given the go-ahead more than two years ago but work never began on the scheme.
Up to 500 jobs could be created during construction of the hotel and conference centre.