Construction will start in January on phase one of the building in south London which will house 18 laboratories and the James Caird Exhibition Hall, showcasing Sir Ernest Shackleton’s lifeboat.
Following the completion of phase one in summer 2015 phase two will begin, adding a further three laboratories, five IT suites and The Auditorium – a public space for both the College and the wider community.
The building has been designed by architects Grimshaw.
McLaren is believed to have beaten competition from Wates, Skanska and Osborne.
The Laboratory is the first major project of a ten year development plan which will see a transformed campus by 2019.
Phil Pringle, McLaren, Managing Director, said: “We are delighted to be part of Dulwich College’s ambitious plans to provide its pupils and the Dulwich community with a teaching and learning environment they deserve.”
McLaren has also won a £13m deal to build a new arts centre in Southampton for the Grosvenor Group.
Construction information specialist Glenigan said the firm beat-off competition from Miller and Bouygues.
McLaren has also been confirmed as main contractor on a £15m deal to build a new distribution centre for Poundland in Harlow, Essex.