The plans will transform hundreds of acres of brownfield land with a new stadium at the heart of the regeneration.
QPR Chairman, Tony Fernandes, said: “We are looking to deliver much more than just a stadium.
“We want to create a new destination that we propose to call ‘New Queens Park’. It will serve as a catalyst for regeneration, creating thousands of new jobs and homes for local people.
“It will be a major transport hub that will connect Old Oak to the rest of London and other major cities across the UK.
“Our new 40,000 seat stadium will become a focal point hosting not just football, but other entertainment and community activities for residents and visitors to enjoy.
“We are very excited about being the driving force behind creating one of the best new urban places in the world, and making this our new home”
The masterplan for the site is being developed by Stadium Capital Development and architect Sir Terry Farrell.
Other members of the professional team include Populous, EC Harris and Savills.
A rival plan for a 45-acre part of the site has also been drawn-up by current owners Cargiant.
Cargiant managing director Tony Mendes said: “Our recent appointment of leading architects and advisors, PLP, First Base and Lipton Rogers, will drive forward the preparation of our plans to deliver significant and successful regeneration.
“We look forward to continuing to work with the GLA, the London Borough of Hammersmith & Fulham and the neighbouring local authorities as well as local residents over the coming months.”