It plans to transform a seven-acre site next to Bristol Temple Meads railway station building modern education and research facilities.
Known as the Temple Quarter Enterprise Campus, construction work is scheduled to get underway in 2019 allowing the campus to open in time for the start of the 2021/22 academic year.
Seven new buildings will transform the former Royal Mail sorting office and part of Arena Island, providing a mix of flexible research and teaching facilities, accommodation for up to 1,500 students and a range of commercial outlets.
Teaching and research will focus on digital technologies, with a new £43m Quantum Technologies Information Centre has already been announced.
The University will also expand its successful Engine Shed enterprise hub and build a new student village together with improvements to the public realm, including new cycle and pedestrian links to the surrounding area and high-quality landscaping.
The University is in the process of appointing a design team and, should its outline planning application be supported by the Council, it will run a public consultation on its detailed plans in Spring 2018.
New Temple Quarter Campus
The Masterplan proposes to comprise nearly 900,000 sq ft of development capacity across both sites within a high-quality public realm.
The main Cattle Market site (left) will house a 8 to 9 storey University main building of 380,000 sq ft. It will also contain a 12-storey University building or student residential building alongside a smaller 9-storey University building.
The other building cluster near the proposed Arena will feature student accommodation in a trio of buildings ranging from 11-25 storeys.