ISG will now focus on design and procurement for the £281m research facility that will serve as a hub for the UK Dementia Research Institute and a new home for the UCL Queen Square Institute of Neurology.

The project team is being led by consultant Arcadis, which will provide project management, cost management and specialist support services.

An existing design team, novated to ISG, will be led by the architectural firm Hawkins/Brown and includes the engineering consultancies Hoare Lea and Rambol.

Building work is due to begin early next year with completion scheduled for late 2023 in readiness for a process of migration and occupation in 2024.

Construction information specialist Glenigan has a rival bidders list of BAM, McAlpine,Bouygues and Laing O’Rourke.

The new development is part of Transforming UCL – a £1.25bn ten-year programme of investment in UCL’s estate to support the university’s continuing growth.

Professor Alan Thompson, Dean of the UCL Faculty of Brain Sciences, said: “The new site will provide a home to three world-leading organisations: the UCL Queen Square Institute of Neurology, the headquarters and UCL component of the UK Dementia Research Institute, and the National Hospital for Neurology and Neurosurgery.

“Bringing these three powerhouses together under one roof will create the leading translational neurology research centre in the world, delivering innovative new discoveries and translating these into treatments that improve the health of patients suffering with dementia and other neurological diseases.

“The new site, within minutes of Queen Square, will provide state-of-the-art facilities and enabling technologies, ensuring that our research scientists have the very best chance of discovering new treatments for these devastating diseases.”

Lee Hutchinson, Managing Director for ISG’s Science and Health Business, said: “We are delighted to have been chosen as the main contractor to design and build UCL’s new world-class facility for neurological research, allowing us to showcase our specialist expertise in this sector.

“At ISG we thrive on fostering innovation and collaboration, and we encourage our people to think differently and deliver smarter environments.

“We’re proud to be working with UCL again to deliver a science and healthcare facility of exceptional quality.

“A vital space will be created for scientists, researchers and clinicians of this world-renowned institute, to discover new ways to diagnose, treat and ultimately prevent one of the greatest health challenges of our time.”