When complete in February 2022, Saddleworth School will accommodate up to 1,500 students aged 11 to 16.
The new secondary school will provide an extra 150 new school places above the existing school which was identified as not fit for purpose.
Phil Shaw, Regional Director at Interserve Construction, said: “This is a really important opportunity for us and the local community. As we venture into uncertain times it is really important we provide opportunities to rebuild the economy through local employment.
“Our appointment by the Department for Education to build the new Saddleworth School further strengthens our position as one of the leading construction companies serving the UK education sector and follows the team’s recent appointment to build the special needs Halcyon Way and Prospect House schools, also in Oldham.”