Designed by Leeds-based architecture practice Cartwright Pickard, the campus will include education facilities, a sports complex, and a residential block.
The college plans to develop a 275,957 sq ft site to the north of the A64 York Road near Leeds city centre on Mabgate.
The currently derelict site has received a number of consents for housing schemes over the years.
The latest proposal would be beneficial to the city’s community, while regenerating a redundant brownfield site.
Bill Jones, Principal at Leeds City College, said: “Our ambition on Mabgate is to deliver a campus that will enhance the learning experience of our students and be widely used by members of the local community.
“These new facilities will complement our existing city centre campuses and provide our students with much needed additional teaching space.
“The development will bring investment and regeneration to the area and is anticipated to act as a catalyst for further investment in this part of Leeds.”