Sister company Create Developments has been granted planning consent for the new seven storey, 147 bedroom hotel after its designs were tweaked following an initial rejection by the council.
The new hotel will be adjacent to Trafford Park and the Trafford Centre and is just five miles from Manchester city centre and 10 miles from Manchester Airport.
The hotel will be predominantly brick-faced, influenced by the architecture of traditional mills associated with the North West of England.
Paul Mathison, CEO for Create Developments said: “As experts in hotel development, we are delighted to be working with Hilton once again.
“Our first Hampton by Hilton hotel development in Blackpool has been so successful, that we are now planning an extension to double its footprint. This new development project in Trafford comes at an exciting period of growth, when Manchester is experiencing a phenomenal construction boom.
“We are very excited to be starting on site soon. This substantial £48m project comes at a time where growth and investment will be key in our bounce-back from the pandemic.
“The approval of the new plans will also help to protect and create new construction jobs and apprenticeships, as well as deliver over 40 new hospitality jobs for local people.”
Create Construction will begin building works Q3 2021 with a build duration of 75 weeks.