The proposals, which have gone in for planning, include building a new college facility, alongside nearly 300 new and affordable homes in several blocks ranging from five to 13 storeys.
Dr Sam Parrett, chief executive of London & South East Education Group, said: “We are delighted to have submitted plans to redevelop our Greenwich Campus.
“This work will enable us to create training facilities which are fit for the future, helping the local economy and community by providing skills and opportunities for generations to come.
“We look forward to progressing our work with L&Q and being part of such positive change in Greenwich.”
Vicky Savage, London managing director at L&Q said that the project partners expected to learn the outcome of the planning application later this year, and plan to open the new campus by September 2025.