ID Manchester, a science and technology hub, will be built on a 26-acre site at its North Campus, near Piccadilly Railway Station in the city.
The proposal envisages delivering 2.6m sq ft of new work space alongside some residential and 3 acres of high-quality public realm on one of the last major development opportunity sites in the city.
The University is expected to confirm the appointment next week after the appointment process stalled during Covid setting plans back.
Stanhope and Bruntwood SciTech JV was in a final head to head with a Peel L&P and Urban Splash pairing.