Located on Deansgate, the overall development is being brought forward by Property Alliance Group in a joint venture with Starwood Capital.
Glasgow-based Calma Group, which was established 10 years ago, is principal contractor for the refurbishment of the former Renaissance Hotel, which is at the heart of the new scheme.
Once the project is complete, the hotel will be relaunched under the SH Hotel & Resorts’ ‘Treehouse’ brand.
Co-founder Andrew Lafferty, said: “This is the most recent win in a string of major new hotel, commercial and housing projects.
“The second of two Treehouse hotels in the UK, it follows Calma delivering the first fast-track scheme for Starwood Capital Group and we are delighted to be invited to undertake another large project for this valued client.”
The joint venture is redeveloping the original hotel as an alternative to demolishing and rebuilding.
This will result in significant environmental benefits, generating around 40% less CO2 compared with constructing a new-build hotel of the same size.
In addition to the redeveloped hotel, the Renaissance development will offer office space, car parking and a residential tower featuring 300 new homes.
Working closely with Manchester City Council, the joint venture is creating a landmark scheme unlocking the potential of a prominent part of Deansgate in the city centre and improving connections to the surrounding area, including Parsonage Gardens and the cathedral.