Construction work was halted last year on The Factory scheme in Hackney Wick which was granted planning permission in 2019.
The £48m mixed-use scheme is designed to reach seven storeys across the site near the Queen Elizabeth Olympic Park.
A Taylor Wimpey spokesperson said: “Following the discovery of a potential structural issue, identified as part of a routine check during the early stages of construction at our development in Monier Road, Hackney Wick, we have taken the decision to demolish the existing concrete structures and rebuild.
“Health and safety is our top priority and this decision has been carefully and thoroughly considered after close consultation with independent structural engineers.
“We are currently finalising a demolition strategy and timeline, and are in the process of communicating with local residents and businesses about our proposals.”