The Gateway scheme will be located on Leeds Street and will provide 656 one-, two- and three-bedroom flats.
These will be built within four towers rising to 15 storeys with two buildings linked by a skybridge.
Legacie Developments recently acquired the site after previous site developer Vinco Group collapsed after gaining planning for a slightly larger residential project on the site which sits within the emerging ‘Northern Quarter’ area, adjacent to the city’s central business district,
The Leeds Street development will feature a garden spa, complete with an infrared sauna, swimming pool, ice bath and oxygen chamber.
There will also be two gyms, two residents’ lounges complete with a cinema room, landscaped gardens, coffee shop and convenience store.
The complex will be a similar scale to Legacie’s Parliament Square development, which is located on the edge of the Baltic Triangle.
Legacie Developments said The Gateway scheme will create more than 250 local construction jobs and 25 apprenticeships.
John Morley, Legacie Developments CEO, said: “We are incredibly excited to be announcing plans for The Gateway and adding to Legacie’s substantial and growing portfolio of quality residential and commercial developments in the region.
“This site has lain vacant for far too long, and I am pleased that we have stepped forward with a scheme that will be a catalyst for further regeneration, provide an economic boost and deliver something the city can be proud of.”