The scheme is London developer Manner’s first in Manchester and will preserve much of the old cotton mill’s existing brick exterior.
Sprouting from the old mill building will rise a 37-storey brick-clad tower incorporating the student rooms. The lower floors of the mill will be occupied with commercial space.
Designed by architects Hodder + Partners, the scheme is timetabled to start construction in early 2025 with completion set for May 2028.
Procurement for the main works contract, expected to cost around £80m, will get underway next month.
Richard James, managing director of Manner, said: “We are confident the redevelopment and the creation of a new public square, independent outlets and public art, will be a fantastic addition to this part of the city centre – delivering a range of benefits for the local community as well as much needed accommodation for students.
“As we prepare for the construction phase to get underway, we will continue our engagement with the local community and help facilitate opportunities to develop plans that will celebrate the historical and cultural significance of this part of the city centre.”